Tom Brady and the New England Patriots head to Arrowhead Stadium to take on Alex Smith and the Kansas City Chiefs.

The New Orleans Saints take on the Dallas Cowboys from AT&T Stadium in Arlington Texas on NBC’s Sunday night football.

The San Francisco 49ers take on the Philadelphia Eagles from Levi’s Stadium in Santa Clara, California.

The Green Bay Packers and the Chicago Bears renew their storied rivalry in a key NFC North matchup from Soldier Field in Chicago.

The Washington Redskins and the New York Giants meet up on Thursday night in a key NFC East divisional game from FedEx Field in Landover, MD.

Jay Cutler and the Chicago Bears take on Geno Smith and the New York Jets from MetLife Stadium in East Rutherford, NJ.

Matt Ryan and the Atlanta Falcons take on the Tampa Bay Buccaneers in an NFC South divisional matchup on Thursday Night Football from the Georgia Dome in Atlanta, GA.

Andrew Luck and the Indianapolis Colts take on the high octane offense of the Philadelphia Eagles on ESPN’s Monday Night Football from Lucas Oil Stadium in Indianapolis.

The San Francisco 49ers play their home opener in brand new Levi’s Stadium when they host the Chicago Bears on NBC’s Sunday Night Football.

The defending champion Seattle Seahawks take on the San Diego Chargers from Qualcomm Stadium in San Diego.